产品描述
每粒胶囊提供 200 毫克增强稳定性形式的 SAMe
- 采用无溶剂制造工艺制造
- 有助于促进健康的情绪平衡
- 有助于缓解骨关节炎引起的疼痛
- 采用低过敏性素食成分制成
SAMe（S-腺苷甲硫氨酸）是存在于所有活细胞中的代谢物。它在 100 多种不同的反应中充当甲基基团的供体，并有助于激素、神经递质、核酸、磷脂和蛋白质的合成、激活和/或代谢。甲基基团在整个身体中充当信号，调节基因表达和细胞功能。40 多项临床研究表明，SAMe 还可以促进健康的情绪平衡。在一项涉及 25 项对照试验和 791 名个体的荟萃分析中，SAMe 为积极情绪提供了统计上显着的支持，据信这是由于它支持神经递质单胺的合成和功能，包括多巴胺和血清素。它还能促进健康的蛋白质周转，维持健康的磷脂甲基化，以支持磷脂酰胆碱的产生和细胞膜的完整性和流动性。研究表明，它还能支持骨关节炎患者的关节灵活性和舒适度。在一项涉及 11 项研究的荟萃分析中，SAMe 为关节功能提供了统计学上显著的支持。据信，它通过支持蛋白聚糖合成，以及帮助稳定和保护蛋白聚糖，来缓解骨关节炎疼痛。
成分
药用成分（每粒胶囊）：SAMe（来自 S-腺苷-L-蛋氨酸二硫酸甲磺酸盐）200 毫克。非药用成分：素食胶囊（羟丙甲纤维素、水）、低过敏性植物纤维素、氧化钙、抗坏血酸棕榈酸酯、氯化钙。
剂量
推荐用途：有助于促进健康的情绪平衡。有助于缓解骨关节炎引起的疼痛。
推荐剂量：成人：为了保持健康的情绪平衡，每天服用 2 粒胶囊 1-3 次。对于骨关节炎疼痛，每天服用 2 粒胶囊 3 次。分次服用，两餐之间服用，或按照医疗保健医生的指示服用。对于骨关节炎疼痛，至少使用 8 周才能看到有益效果。如果超过 12 周，请咨询医疗保健医生。
注意事项
警告：如果您怀孕、哺乳或被诊断患有躁郁症，请勿使用。如果您正在服用抗抑郁药、肝毒性药物或单胺氧化酶 (MAO) 抑制剂等药物，请在使用前咨询医疗保健医生。请勿在晚上服用，因为该产品可能会导致焦虑、不安和失眠。如果症状持续或恶化，请咨询医疗保健医生。有些人可能会出现轻度胃肠不适、焦虑、不安、失眠、肌肉运动过度和轻躁狂，在这种情况下，请停止使用并咨询医疗保健医生。
Product Description
Provides 200 mg per capsule of enhanced-stability form SAMe
- Manufactured using a solvent-free manufacturing process
- Helps to promote healthy mood balance
- Helps relieve pain due to osteoarthritis
- Made with hypoallergenic, vegan ingredients
SAMe (S-adenosylmethionine) is a metabolite present in all living cells. It functions as a donor of methyl groups in over 100 different reactions and contributes to the synthesis, activation and/or metabolism of hormones, neurotransmitters, nucleic acids, phospholipids, and proteins. Methyl groups act as a signal throughout the body, regulating genetic expression and cellular function. SAMe also promotes healthy mood balance, as indicated in over 40 clinical studies. In a meta-analysis involving 25 controlled trials and 791 individuals, SAMe offered statistically significant support for positive mood, believed to be due to its support for neurotransmitter monoamine synthesis and function, including dopamine and serotonin. It also promotes healthy protein turnover and maintains healthy phospholipid methylation to support phosphatidylcholine production and cellular membrane integrity and fluidity. Studies suggest it supports joint flexibility and comfort in individuals with osteoarthritis as well. In a meta-analysis involving 11 studies, SAMe offered statistically significant support for joint function. It is believed to relieve osteoarthritis pain by supporting proteoglycan synthesis, as well as helping to stabilize and protect the proteoglycans.
Ingredients
Medicinal Ingredients(per capsule): SAMe (from S-Adenosyl-L-methionine disulfate tosylate) 200 mg. Non-Medicinal Ingredients: Vegetarian capsule (hypromellose, water), Hypoallergenic plant cellulose, Calcium oxide, Ascorbyl palmitate, Calcium chloride.
Dosing
Recommended Use: Helps to promote healthy mood balance. Helps relieve pain due to osteoarthritis. Recommended Dose:Adults: For healthy mood balance, take 2 capsules 1-3 times daily. For osteoarthritic pain, take 2 capsules 3 times daily. Take in divided doses, between meals, or as directed by a healthcare practitioner. For osteoarthritic pain, use for a minimum of 8 weeks to see beneficial effects. Consult a healthcare practitioner for use beyond 12 weeks.
Cautions
Warning: Do not use if you are pregnant, breastfeeding or have been diagnosed with bipolar disorder. Consult a healthcare practitioner prior to use if you are taking medication such as antidepressants, hepatoxic drugs or monoamine oxidase (MAO) inhibitors. Do not take at night, as the product may cause anxiety, restlessness and insomnia. Consult a healthcare practitioner if symptoms persist or worsen. Some people may experience mild gastrointestinal upsets, anxiety, restlessness, insomnia, hyperactive muscle movement, and hypomania, in which case discontinue use and consult a healthcare practitioner.
*These statements have not been evaluated by the Food and Drug Administration. This product is not in tended to diagnose, treat, cure, or prevent any disease.
Some formulas may be slightly different outside Canada and the US.